cfDNA Multiplexed Standards (125ng in 5ml Plasma, 3% AF)
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Multiplexed ctDNA fragments (~150bp) mixed with nucleosomally fragmented WT cfDNA background in human plasma.
cfDNA Reference Standards are highly characterized, biologically relevant materials used to assess the performance of cfDNA assays that detect somatic mutations via PCR, Next Generation Sequencing (NGS), or other novel readout methods.
Why use cfDNA controls and reagents?
Human plasma is a complicated matrix and cfDNA is often present at very low levels. ZeptoMetrix delivers high sensitivity for detection of rare cfDNA presence through unique standards and controls that mimic human specimens.
Systemic lack of TRUE standards and controls results in:
– Poor clinical sensitivity
– Discordance among assays – despite enhancement in sequencing detection, there still remain rampant discordance among liquid biopsy assays. Assays developed in 2019 are no more sensitive than assays developed in 2017.
-20° C.
