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Cell-free DNA Controls (cfDNA)

Oncology Controls for Molecular Testing

cfDNA controls or reference standards are highly characterized, biologically relevant materials used to assess the performance of assays that detect somatic mutations in cfDNA via PCR, Next Generation Sequencing (NGS), or other novel readout methods.

Why use cfDNA controls and reagents?

– ZeptoMetrix controls help ensure the accuracy of the highly sensitive assays needed for the detection of cfDNA in plasma

– Nucleosomal fragmentation results in a range of cfDNA fragment sizes that mimic patient samples

– Available as concentrated DNA in TE buffer or blended into DNA-depleted plasma as a ready-to-use, full-process control

– Highly customizable product configuration

cfDNA Controls for Non-Invasive Prenatal Testing (NIPT)

ZeptoMetrix offers patient-like cfDNA reference materials for Trisomy 13, 18, and 21 for assay development, validation, and routine run QC for NIPT assays.

New Product!
The first comprehensive ESR1 Control covering 16 ESR1 mutations. Comprehensive ESR1 Control Kit for Oncology Testing Vial 1-ESR1 Mutations S463P L536H Y537S D538G Vial 2-ESR1 Mutations E380Q P535H L536P Y537C Vial 3-ESR1 Mutations S463C L536R Y537N K303R Vial 4-ESR1 Mutations S463F V534E L536Q V422del

Showing all 13 results

cfDNA Multiplexed Standards (125ng in 5ml Plasma, 3% AF)
cfgDNA Normal Female Standard Background (1ug in TE buffer)
cfgDNA Normal Female Standard WT Background (250ng spiked in 5ml Plasma)
ESR1 Control Kit (4 Vials + wt control)
Multiplexed-50 cfDNA Standard at 3%AF, 1ug in TE
Trisomy 13 Standard for counting based assays, 5% fetal fraction, 125ng in 5mL plasma
Trisomy 13 Standard for counting based assays, 5% fetal fraction, 1ug in TE
Trisomy 13, 18 & 21 Standard for counting based assays, 5% fetal fraction, 125ng in 5mL plasma
Trisomy 13, 18 & 21 Standard for counting based assays, 5% fetal fraction, 1ug in TE
Trisomy 18 Standard for counting based assays, 5% fetal fraction, 125ng in 5mL plasma
Trisomy 18 Standard for counting based assays, 5% fetal fraction, 1ug in TE
Trisomy 21 Standard for counting based assays, 5% fetal fraction, 125ng in 5mL plasma
Trisomy 21 Standard for counting based assays, 5% fetal fraction, 1ug in TE
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