Unlock special prices! Log in or register to reveal exclusive offers.
01aaa_7839-20-1-jpg

Anti-PON1 Clone KRJ2 (1 mg)

The prices will be displayed on the checkout.

Categories: , Tag:

PON1 (arylesterase/paraoxonase) is a polymorphic enzyme closely associated with high-density lipoproteins (HDL). It is located on chromosome 7 along with 2 other paraoxanase genes, PON2 and PON3. It is a 355 amino acid, 43 kDa glycoprotein produced in the liver and secreted into the bloodstream. Gene polymorphisms occur in both coding and non-coding regions. Two major polymorphisms in the coding region are L55M and Q192R. Q192R polymorphisms result in three major functional phenotypes Q/Q, Q/R and RR. PON1 hydrolyses organophosphates and prevents the oxidation of low-density lipoproteins (LDL). It may inhibit the progression of atherosclerosis by inhibition of LDL oxidation. Levels of PON1 in serum vary among individuals and are decreased in chronic renal failure, liver cirrhosis, diabetes, peripheral neuropathy, and familial hypercholesterolemia.

-20° C.
Product Insert.pdf

Material Safety Data Sheet.pdf

FacebookTwitterLinkedin

Additional Information

Product Code

Origin

USA

BTN - HC

Size

KGS

Shipping Conditions

0
    Your Cart
    Your cart is emptyReturn to Shop

    Unlock special prices!
    Log in or register to reveal exclusive offers.